These are my MOST often used keybindings that I use in tmux. They allow me to jump between splits with ease with a vim style layout. I can hold mod and jump between panes with a familiar arrow key.
bind -n M-h select-pane -L bind -n M-l select-pane -R bind -n M-k select-pane -U bind -n M-j select-pane -D
for more information on how I navigate tmux, check out this full post